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Research Opportunities

  • Fellows are encouraged to participate in on-going or original research projects to graduate from the program.
    • The research faculty, as well as the physicians, serve as mentors for these projects.
    • Presentations at national meetings and manuscript submissions are anticipated from these activities.
    • All presenting fellows attend the annual American Academy of Sleep Medicine (AASM) and Associated Professional Sleep Societies LLC (APSS) meeting.
  • If approved for research, there will be a half day, per week, given to the fellows.
  • This research must be an IRB approved or ongoing study.

There are currently ongoing Research Projects in the areas:

  • Pharmacology of sleep

  • Long-term effect of sleep medications

  • Insomnia

  • Sleep disordered breathing and COPD

  • Hypersomnia disorders

  • Effects of Shift work

  • Pregnancy and sleep disorders

Past Sleep Medicine Research Projects (2025)

Publications

  1. Aboukasm, A., Reffi, A. N., & Drake, C. L. (2025). Z hypnotics in the management of narcolepsy: A case series. Journal of Clinical Sleep Medicine.

  2. Aggarwal B, Gao Y, Alfini A, Azarbarzin A, Anafi RC, Glazer Baron K, Bautch VL, Bowles N, Broussard JL, Brown M, Cheng P, Cook SH, Cortese R, Fernandez FX, Galis Z, Johnson DA, Jelic S, Lipton JO, Lutsey PL, Miao Q, Ordovas JM, Prather AA, Swirski FK, Tasali E, Vargas I, Grandner MA, Lloyd-Jones D. (2025). Sleep and circadian rhythms in cardiovascular resilience: mechanisms, implications, and a roadmap for research and interventions. Nature Reviews Cardiology, 23(2):116–130. PMID: 40968347.

  3. Cole TA, Ong LE, Carsten B, Tappenden PC, Reffi AN, Orcutt HK. (2025). Trauma typologies and internalizing psychopathology: A hierarchical perspective. Psychological Trauma. PMID: 39899051.

  4. Coyne P, Jennings MB, Santarossa S, Murphy D, Zreik M, Bryans H, Drake C, Walch O, Cheng P. (2025). Arcashift™ digital circadian intervention for shift work disorder. BMC Digital Health, 3(1):25. PMID: 40740477.

  5. Drake CL, Yardley J, Pinner K, Moline M, Malhotra M. (2025). Perception of lemborexant effectiveness. Nature and Science of Sleep, 17:557–570. PMID: 40225286.

  6. Ellis JG, Alfonso-Miller P, Cheng P, Bastien CH, Altena E, Grandner MA. (2025). Managing insomnia trajectory. Journal of Behavioral and Cognitive Therapy, 100540.

  7. Espie CA, Grandner MA, Drake CL. (2025). CBT-I delivery by healthcare providers. Sleep, 48(10). PMID: 40396901.

  8. Gumenyuk V, Murman DL, Roth T, et al. (2025). Subjective vs objective sleep discrepancies and MCI. Sleep Medicine Research, 16(1):33–41.

  9. Jennings MB, Kalmbach DA, Reffi AN, et al. (2025). Digital CBT-I to prevent pain interference. Behavioral Sleep Medicine, 23(5):1–13. PMID: 40324067.

  10. Kalmbach DA, Ong JC, Cheng P, et al. (2025). Telemedicine CBT-I and PUMAS for prenatal insomnia. Sleep Medicine, 133:106570. PMID: 40413907.

  11. Khoshakhlagh AH, Yazdanirad S, Drake C, Iqal J, Bui D. (2025). VOC exposure and sleep problems. Public Health Reviews, 46:1608224. PMID: 41079250.

  12. Khoshakhlagh AH, Yazdanirad S, Gruszecka-Kosowska A, Drake CL, Emerson W. (2025). Aerosol exposure and sleep problems: meta-analysis. PLoS One, 20(5):e0321515. PMID: 40343941.

  13. Leary EB, Van Dongen HPA, Drake C, et al. (2025). Solriamfetol and cognitive performance in OSA. Postgraduate Medicine, 137(3–4):209–219. PMID: 40325548.

  14. Mahr G, Reffi AN, Moore DA, Drake CL. (2025). Depth psychology and acute trauma. Journal of Jungian Scholarly Studies.

  15. Miller CB, Bradley D, Wood I, et al. (2025). Digital CBT-I implementation and healthcare utilization. Implementation Research and Practice, 6:26334895251386306. PMID: 41181516.

  16. Olff M, Hein I, Amstadter AB, et al. (2025). Psychotraumatology review. European Journal of Psychotraumatology, 16(1):2458406. PMID: 39912534.

  17. Ortiz LE, Morse AM, Thorpy MJ, et al. (2025). Sodium oxybate for narcolepsy. Journal of Sleep Research, e70189. PMID: 40851446.

  18. Palagini L, Bruni O, Colizzi M, et al. (2025). Maternal insomnia and newborn sleep. Sleep Medicine, 134:106732. PMID: 40795452.

  19. Reffi AN, Cheng P, Kalmbach DA, et al. (in press). Nightmares after trauma (UNiTED study). European Journal of Psychotraumatology. PMID: 39376120.

  20. Reffi AN, Drake CL. (2025). Behavioral components of CBT-I. In: Cognitive Behavioral Therapy for Insomnia in Comorbid Conditions. APA Publishing.

  21. Reffi AN, Kalmbach DA, Cheng P, et al. (2025). Sleep reactivity and PTSD risk. Psychological Trauma. PMID: 41343381.

  22. Reffi AN, Kalmbach DA, Cheng P, et al. (2025). Nightmares, insomnia, and suicidal ideation. Journal of Clinical Sleep Medicine, 21(9):1519–1527. PMID: 40265245.

  23. Roehrs T, Koshorek G, Sibai M, et al. (2025). Difficulty discontinuing hypnotics. Psychopharmacology, 242(10):2303–2311. PMID: 40342163.

  24. Roth T. (2025). Clinical utility of oxybates. CNS Drugs, 39(Suppl 1):37–51. PMID: 40111735.

  26. Shaif NAS, Lim J, Reffi AN, et al. (2025). Sleep reactivity and cognitive arousal. Journal of Sleep Research, e70220. PMID: 41084944.

  27. Weed L, Jamgochian A, St Hilaire MA, et al. (2025). Circadian phase estimation via wearables. Journal of Biological Rhythms. PMID: 41342262.

 

Abstracts

  1. Afaneh H, Hirata M, Kalmbach D, Cheng P, Pitts D. Financial Toxicity, Racial Disparities, and Healthcare Access in Pregnant Women with Insomnia. Sleep 2025;48:A260.
  2. Belevender C, Ozeir S, Bugazia S, Badhwar A, Shakaroun D, Carlin A, Roehrs T, Skiba V. Predicting CPAP adherence following bariatric surgery. Sleep 2025;48:A585.
  3. Belevender C, Ozeir S, Korpole P, Jaziri M, Reffi A, McLellan B, Bazan L. Success rate of obstructive sleep apnea diagnosis in a direct referral program versus standard care. Sleep 2025;48:A586.
  4. Bogan R, Roth T, Thorpy M, Kushida C, Gudeman J. Clinically meaningful improvement in daytime sleepiness with ON-SXB in narcolepsy. Sleep 2025;48:A361.
  5. Chavez AG, Xu TFY, Hirata M, Kalmbach D, Cheng PL, Drake C, Pitts D. Implementability of a perinatal sleep clinic. Sleep 2025;48:A565.
  6. Corser B, Plante D, Drake C, Bogan R, Dauvilliers Y, et al. Effect of pitolisant in idiopathic hypersomnia (open-label phase 3). Sleep 2025;48:A376.
  7. Dauvilliers Y, Plante D, Corser B, Drake C, Bogan R, et al. Long-term safety and effectiveness of pitolisant in idiopathic hypersomnia. Sleep 2025;48:A376–A377.
  8. Dauvilliers Y, Plazzi G, Plante D, Mignot E, Roth T, et al. Phase 2a study of ORX750 in narcolepsy and idiopathic hypersomnia. Sleep 2025;48:A373–A374.
  9. Dauvilliers Y, Thorpy M, Roth T, Kushida C, Morse A, et al. Efficacy of once-nightly sodium oxybate on disrupted sleep. Sleep 2025;48:A362–A363.
  10. Hirata M, Afaneh H, Kapoor I, Kalmbach D, Reffi A, et al. Trait mindfulness and nocturnal cognitive arousal in pregnancy/postpartum insomnia. Sleep 2025;48:A246.
  11. Jennings M, Treger M, Zhou ER, Cheng PL. Accessibility of behavioral insomnia treatment in the US. Sleep 2025;48:A246.
  12. Kapoor I, Treger M, Van Rossen V, Fellman-Couture C, Wernette E, Drake C, Cheng PL. Occupational prestige and sleep. Sleep 2025;48:A208–A209.
  13. Kaur S, Shakaroun D, Badhwar A, Bugazia S, Childers K, Roehrs T, Skiba V, Carlin A. PAP treatment impact on bariatric surgery PACU management. Surgery for Obesity and Related Diseases 2025;21(6):S30.
  14. Korpole P, Jaffery SH, Arcila-Londono X, Bazan LF. PAP settings in bulbar-onset ALS requiring NIV. American Journal of Respiratory and Critical Care Medicine 2025;211:1.
  15. Mahr G, Reffi A, Jankowiak L, Moore D, Drake C. Emotional dream content in acute trauma patients. Sleep 2025;48:A509.
  16. McCray C, Wernette E, Xu T, Ravindran S, Drake C, Cheng P. Social functioning and depression reduction in CBT-I. Sleep 2025;48:A526.
  17. Miller C, Bradley D, Wood I, Willens D, Nair A, et al. Digital CBT-I and reduced healthcare use (Henry Ford Health). Sleep 2025;48:A236.
  18. Ojeda IC, Al-Nesf MAY, Ibrahim T, et al. Sleep disorders and quality of life in chronic urticaria. Journal of Allergy and Clinical Immunology 2025;155(2):1.
  19. Ojeda IC, Guidos G, Beas IM, et al. Hereditary angioedema severity and sleep disorders (HAE SLEEP study). Journal of Allergy and Clinical Immunology 2025;155(2):1.
  20. Ozeir S, Belevender C, Bugazia S, Badhwar A, Shakaroun D, Carlin A, Roehrs T, Skiba V. Predictors of PAP adherence post-bariatric surgery. Sleep 2025;48:A585.
  21. Ozeir S, Belevender C, Korpole P, Jaziri M, McLellan B, Reffi A, Bazan L. Time to OSA diagnosis: direct referral vs standard care. Sleep 2025;48:A586.
  22. Plante D, Corser B, Drake C, Bogan R, Dauvilliers Y, et al. Pitolisant effects during double-blind withdrawal phase. Sleep 2025;48:A375–A376.
  23. Pockrass A, Treger M, Peeran I, Russell J, Wernette E, Drake C, Cheng P. Sleep reactivity and duration of night shift work. Sleep 2025;48:A217–A218.
  24. Ravindran S, Treger M, Russell J, Coyne P, McCray C, Drake C, Walch O, Cheng P. User experience of circadian alignment mobile app. Sleep 2025;48:A385.
  25. Reffi A, Jankowiak L, Moore D, Basarkod S, Jovanovic T, Cheng PL, Hsieh HF, Drake C. Fear of sleep predicting nightmare severity after trauma. Sleep 2025;48:A510.
  26. Reffi A, Moore D, Jankowiak L, Drake C. Lifetime trauma and sleep reactivity in acute trauma patients. Sleep 2025;48:A228–A229.
  27. Roehrs T, Roth T. BzRA receptor specificity and rebound insomnia. Sleep 2025;48:A238–A239.
  28. Roehrs T, Sibai M, Tabor A, Roth T. Mood and difficulty discontinuing chronic hypnotics. Drug and Alcohol Dependence 2025;267.
  29. Roth T, Ibrahim S, Morse A, Gudeman J, Dauvilliers Y. MWT vs ESS correlation in REST-ON. Sleep 2025;48:A373.
  30. Russell J, Treger M, Kalmbach D, Drake C, Cheng P. Digital CBT-I as a scalable workplace solution. Sleep 2025;48:A89.
  31. Thorpy M, Mundt J, Ibrahim S, Kushida C, Lavender M, Gudeman J, Roth T. Hallucination types in narcolepsy (REST-ON). Sleep 2025;48:A361–A362.
  32. Treger M, Pockrass A, Peeran I, Van Rossen V, Wernette E, Drake C, Walch O, Cheng P. Apple Watch to optimize light therapy for shift workers. Sleep 2025;48:A383–A384.
  33. Van Rossen V, Treger M, Kapoor I, Fellman-Couture C, Drake C, Cheng P. Digital CBT-I accessibility for the deaf community. Sleep 2025;48:A256.
  34. Wernette E, Walch O, Drake C, Cheng P. Multi-device machine learning for home sleep tracking. Sleep 2025;48:A192–A193.


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