FISH Probes

Oncology - interphase analysis

1p36/1q25 -19p13/19q13 Glioma/Astrocytoma

1q21.3/1p32.3 CKS1B/CDKN2C MM

n-MYC 2p24.1 neuroblastoma

2p11.2 IGK breakapart

2p23 ALK t(2;5) or inv(2) probe

inv(3)(q26) EVI1 break apart probe

3q27 BCL6 break apart probe

3q28 TP63 breakapart

4/10/17 Centromeres - ALL

4q12 FIP1L1::CHIC2::PDGFRA

t(4;14) IGH::FGFR3 (MM)

5q33 PDGFRb break apart probe

-5/5q- (5q deletion probe)

-7/7q- (7q deletion probe)

7 MET amplification probe

6p21.1 TFEB break apart

6p25.3 DUSP22::IRF4 NHL

t(6;14) CCND3::IGH (MM)

8 centromere enumeration

8p12 FGFR1 break apart/enumeration

8q24 MYC/8cen amplification probe

8q24 MYC Break apart

t(8;14) Burkitt

t(8;21) AML-M2

t(9;22) CML or ALL

9p21 CDKN2A/9cen

9p24.1 JAK2 breakapart

9q34 deletion probe

10p11.21 RET breakapart probe

11q23 MLL translocation/deletion probe

11q22.3 ATM deletion probe

t(11;14) Mantle cell

t(11;18) BIRC3::MALT1

12 centromere enumeration

12p13 ETV6 ALL/Sarcoma

12q13 DDIT3 (CHOP) Sarcoma

t(12;21) childhood ALL

13/21 - RB1 deletion / 21 enumeration

13q14 RB1 deletion (MM)

13q14.3 D13S319 deletion (CLL/MDS)

13q34 deletion probe

14q11.2 TRAD breakapart

14q32.3 IGH break apart probe

t(14;16) IGH::MAF (MM)

t(14 ;20) IGH::MAFB (MM)

t(14;18) IGH::BCL2 Follicular cell

t(15;17) AML-M3

16p11 FUS Sarcoma

inv(16) AML-M4

17q21 RARA break apart

17p13.1 (p53) deletion

18q11.2 SS18 (SYT) Sarcoma

18q21 MALT1 break apart lymphoma

22q11.21-q11.23 IGL breakapart

20q12 D20S108 deletion probe

22q12 EWSR1 Sarcoma

Xp22.33/Yp11.32 CRLF2 breakapart

Xp11.2 TFE3 break apart

X-Y sex mismatched bmt

Microdeletion - metaphase analysis

4p16.3 Wolf-Hirschhorn (WHS)

5p Cri du Chat (D5S23(g)/EGR1(or))

7q Williams Syndrome (WMS)

15q SNRPN – Prader Willi

15q D15S10 – Angelman

17p11.2 Smith-Magenis (SMS)

17p13.3 Lissencephaly (LIS1)

22q DiGeorge Syndrome (DGS – HIRA/ARSA)

Xp22 Kallmann Syndrome (KAL)

Xp22.3 STS (Steriod Sulfatase)

X-linked Ichthyosis

Xq13 XIST

Yqh (aqua)

Yp11.3 SRY region

Acrocentric (beta-satellite) probe

 

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