National CSI

The National Cardiogenic Shock Initiative (NCSI) results demonstrated a survival rate of 71%
to hospital discharge in 406 patients who presented with acute myocardial infarction (AMI) complicated by cardiogenic shock at 80 hospitals in 29 states and were treated with the protocol.

Researchers announced the trial results on April 28, 2021 at the
Society for Cardiovascular Angiography and Interventions (SCAI) 2021 Scientific Sessions.



The Detroit Cardiogenic Shock Initiative (CSI) is now the National Cardiogenic Shock Initiative. Started by William O’Neill, M.D. in 2016, National CSI began as a collaboration between four different Detroit-area hospital systems with the goal of improving mortality in patients suffering from Cardiogenic Shock. Since then, a common treatment and data collection protocol is being used at hospital systems across the country to track the results and measure success. The life-saving Initiative now includes a variety of hospitals nationwide.

Collaborating Hospitals

Partnering hospital systems use a defined protocol for treatment of AMI patients in cardiogenic shock which includes quick placement of the lmpella heart pump, PCI, and right heart monitoring to rapidly reduce the use of inotropes. Quality data is collected on each patient. The initial pilot study has shown improvement in survival rates from 50% to 72% as presented at ACC.17.


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